Recently, our latest research paper "Modulating the Hydrophilic Hydrophobic Microenvironment of MOF Stabilized Pt Nanozymes: The Role of H2O in the Peroxidase Like Catalyzed Reaction" was published online in Advanced Functional Materials (IF: 18.5). Jiangsu University is the first completion unit, and our master's student Shen Bingqing is the first author. Our teachers Liu Zhenjiang and Li Weibin are co corresponding authors. This work has also received support from Professor Li Longhua of Jiangsu University and Professor Zhu Chengzhou of Central China Normal University.

Rapid and sensitive detection of organophosphorus pesticides is crucial for protecting human health and environmental safety. Biosensors have attracted much attention in fields such as environmental detection and medical diagnosis due to their high sensitivity and fast response. The activity of nano enzymes, which are the core components, still needs to be improved. Therefore, developing new nano enzymes with high stability and activity is the key to improving pesticide detection efficiency. Research has found that strategies to enhance the catalytic performance of nanoenzymes include not only regulating the electronic structure of the active center, but also simulating the hydrophobic binding pockets of natural enzymes. However, the influence of water molecules in hydrophilic hydrophobic microenvironments on catalyst performance has not received sufficient attention. Therefore, a deeper understanding of how water molecules specifically affect nanoenzyme catalytic reactions is of great significance for designing efficient and economical nanoenzymes.

This study provides new insights into the complex role of water molecules in pod like catalytic systems and valuable guidance for understanding the mechanisms of other multiphase catalytic systems.

The research results have been supported by projects such as the National Natural Science Foundation of China. Article link: https://onlinelibrary.wiley.com/doi/10.1002/adfm.202415854