Recently, our faculty and students published the latest research findings titled "Unnatural Direct Interspecific Electron Transfer Enabled by Living Cell Cell Click Chemistry" in the journal Angewandte Chemie International Edition (IF: 16.6). Jiangsu University is the first completion unit and the only corresponding unit. Yong Yangchun from the Energy Research Institute/Biomass Energy Research Institute is the only corresponding author. Zhao Yicheng, a master's student from the School of Environmental and Safety Engineering, and teacher Sha Chong are co first authors.

Based on the concept of "building knowledge" in synthetic biology, this study provides direct evidence for DIET mediated by C-type cytochrome on the outer membrane of cells, indicating the possible existence of more sophisticated DIET pathways in nature, and opening up new ideas for the study of interspecies electron transfer mechanisms. Furthermore, based on the concept of "building for use", this study proposes the idea of "cellular magpie bridge engineering", which will provide a solution for DIET process regulation and new ideas for the application of microbial electron transfer engineering.

This study was supported by the National Key Research and Development Program, the Jiangsu Province Dual Carbon Science and Technology Special Project, and the National Natural Science Foundation of China.

Full text link: https://onlinelibrary.wiley.com/doi/10.1002/anie.202402318