朱道辰，研究员/教授, 博士生导师
E-mail：dczhucn@ujs.educn
个人简介：日本神户大学理学博士，江苏大学生物质能源研究院执行院长，石油和化工行业人工智能设计与生物质过程仿生重实验室副主任，中巴“合成生物学与生物质炼制国际合作联合实验室”主任，固体废弃物能源转化与利用研究所所长，江苏省“六大高峰人才”，江苏省“双创博士”，江苏省“双创团队”骨干，江苏大学优秀教师。入选全球前2%顶尖科学家榜单（斯坦福大学/爱思唯尔）。学术兼职：江苏省海洋学会理事，中国生物发酵产业协会酵素分会专家委员会副秘书长，江苏省生物技术协会合成生物学专委会副主任，Heliyon、Frontiers in Microbiology等SCI期刊副主编，Insect Science，Frontiers in Bioengineering and Biotechnology等期刊客座编辑。主持和参与国家重点研发计划，国家重点研发-政府间国际合作重点项目、江苏省重点研发计划、江苏省碳达峰碳中和科技创新专项、国家自然基金、教育部留学回国人员启动基金、江苏省自然基金、广东省自然基金、江苏省农业科技自主创新重点项目等省部级项目20余项，主持企业横向课题10余项。近年来以第一作者或通讯作者发表包括Biotech Adv，Renew Sust Energ Rew、Green Chem、Bioresource Technol、J Clean Prod等国际知名top期刊在内的SCI论文140余篇，H-index 35。已授权发明专利12项， PCT专利授权1项。在Springer，Elsevier、Wiley等出版社出版英文编/专著5部。
工作经历
2009年12月-至今，江苏大学
2014年2月-9月，美国华盛顿州立大学任访问学者
研究领域：
1、微生物与酶资源挖掘及其在环境、农业、生物医药等领域应用；
2、生物基化学品的生物转化及加工过程，天然产物合成及代谢调控与其在环境修复、生物医药、功能食品方面应用;
3、农林废弃生物质资源综合利用，生物基材料制备与功能研究、3D打印生物基可降解材料；
4、环境修复与新污染物（如PFAS）生物降解及生态治理。
近5年发表的部分SCI论文：
1. Zhong Z, Gorish BM, Bai Y, Abdelmula WI, Dang W, Zhu, D.* (2025). Predicting lignin removal efficiency in deep eutectic solvent-based biomass fractionation: an explainable machine learning approach. Green Chemistry. https://doi.org/10.1039/D5GC02370J（封底文章）
2. Ahmad F, Bodawatta K, Poulsen M, Zhu, D.* (2025). Advancing approaches to cultivate industrially and ecologically relevant microorganisms from termite guts. Biotechnology Advances. 108676.21. https://doi.org/10.1016/j.biotechadv.2025.108676
3. Gorish, B. M. T., Abdelmula, W. I. Y., Wenqian, D., & Zhu, D.* (2025). Multifunctional lignin-gum Arabic nanocomposites: Green nanoarchitectonics via ultrasonic-assisted laccase catalysis for antimicrobial, antioxidant, and antidiabetic therapies. Biomaterials Advances, 177, 214390.
4. Zhe, L., Sethupathy, S., Wenqian, D., Hu, J., & Zhu, D.* (2025). Lignin valorization through microbial production of polyhydroxyalkanoates: Recent trends, challenges and opportunities. Green Chemistry.27, 5920-5946.
5. Abdelmula, W. I. Y., Gorish, B. M. T., Dar, M. A., Sethupathy, S., Altayeb, H. N., Han, S., ... & Zhu, D.* (2025). Lignin: A green material for sustainable antiviral application. Sustainable Materials and Technologies, e01411.
6. Suboktagin, S., Ullah, M. W., Sethupathy, S., Keerio, H. A., Alabbosh, K. F., Khan, K. A., & Zhu, D.* (2025). Microbial cell factories for bioconversion of lignin to vanillin-Challenges and opportunities: A review. International Journal of Biological Macromolecules, 142805.
7. Ahmad, F., Jinhao, H., Nawaz, M. Z., Dar, M. A., Nasser, R., Haider, S. Z., ... & Zhu, D.* (2025). Lignin disruption and ligninolytic enzyme activity in the symbiotic system of the Macrotermes barneyi termite. Insect Science. https://doi.org/10.1111/1744-7917.70026
8. Xingrong, L., Gorish, B. M. T., Qaria, M. A., Hussain, A., Abdelmula, W. I. Y., & Zhu, D.* (2025). Unlocking Ectoine’s Postbiotic Therapeutic Promise: Mechanisms, Applications, and Future Directions. Probiotics and Antimicrobial Proteins, 1-26.
9. Ali, M. Y., Abdalla, M., Roumia, A. F., Tammam, M. A., Ramadan, M. F., Edrees, M. A. H., ... & Zhu, D.* (2025). Boosting the catalytic efficiency of UGT51 for efficient production of rare ginsenoside Rh2. Folia Microbiologica, 1-12.
10. Jalal, A., Wang, Y., Cai, C., Ayaz, A., Alabbosh, K. F., Khan, K. A., ... & Zhu, D.* (2025). The Architecture of Adaptive Lignin Biosynthesis Navigating Environmental Stresses in Plants. Journal of Agronomy and Crop Science, 211(1), e70012.
11. Ma, K., Uddin, N., Jin, H., Ullah, M. W., Shah, S. W. A., Sakrabani, R., & Zhu, D.* (2025). Lignin-based cryogels for advancing sustainable crop production via enhanced nutrient accessibility and growth efficiency. International Journal of Biological Macromolecules, 287, 138613.
12. Abdelmula, W. I. Y., Gorish, B. M. T., Sethupathy, S., Zijing, Z., Altayeb, H. N., & Zhu, D.* (2025). Green synthesis of polyphenol-grafted lignin nanoparticles and their application as sustainable anti-acne, antioxidant, and UV-blocking agents. Colloids and Surfaces B: Biointerfaces, 245, 114309.
13. Zhuang, Z., Sethupathy, S., Bajón-Fernández, Y., Ali, S., Niu, L., & Zhu, D.* (2025). Microbial Chemotaxis in Degradation of Xenobiotics: Current Trends and Opportunities. Microbiological Research, 290, 127935.
14. Gao, L., Jiang, F., Zhang, Z., Bao, T., Zhu, D.*, & Wu, X*. (2024). Unlocking lignin valorization and harnessing lignin-based raw materials for bio-manufacturing. Science China Life Sciences, 1-16.
15. Xu, L., Sethupathy, S., Liang, Z., Zhuang, Z., Zhang, Y., Sun, J., & Zhu, D.* (2024). NAD+ regeneration-coupled enzymatic bioconversion of lignin-derived vanillin into vanillic acid: A cleaner production approach. Industrial Crops and Products, 222, 119921.
16. Liaqat, F., Khazi, M. I., Ji, T., Liaqat, N., Le, Y., Al-Ghanim, K. A., ... & Zhu, D.* (2024). Biovalorization of lignin-derived substrates to vanillylamine via a self-sufficient amino donor and cofactor recycling whole-cell platform. Environmental Research, 263, 120112.
17. Nawaz, M. Z., Khalid, H. R., Mirza, M. U., Xu, L., Haider, S. Z., Al-Ghanim, K. A., ... & Zhu, D.* (2024). Elucidating the bioremediation potential of laccase and peroxidase enzymes from Bacillus ligniniphilus L1 in antibiotic degradation: A computationally guided study. Bioresource Technology, 413, 131520.
18. Nawaz, M. Z., Haider, S. Z., Zhe, L., Mirza, M. U., Khalid, H. R., Alghamdi, H. A., & Zhu, D.* (2024). Evaluating the estrogen degradation potential of laccase and peroxidase from Bacillus ligniniphilus L1 through integrated computational and experimental approaches. International Journal of Biological Macromolecules, 137187.
19. Rahman, M. U., Ullah, M. W., Alabbosh, K. F., Shah, J. A., Muhammad, N., Shah, S. W. A., ... & Zhu, D.* (2024). Lignin valorization through the oxidative activity of β-etherases: Recent advances and perspectives. International Journal of Biological Macromolecules, 136383.
20. Hossain, M. M., Tripty, S. J., Shishir, M. Z. A., Wang, S., Hossain, I., Geng, A., ... & Zhu, D.* (2024). Malondialdehyde and heavy metal contents in Piper betel: possible risks of Heavy metals in Human Health. Journal of Food Composition and Analysis, 134, 106540.
21. Uddin, N., Li, X., Ullah, M. W., Sethupathy, S., Chen, F., Yang, B., & Zhu, D.* (2024). Unlocking the Potential of Catechyl Lignin: Molecular Regulation of Biosynthesis, Structural Organization, And Valorization. ACS Sustainable Chemistry & Engineering, 12(33), 12289-12305.
22. Gao, J., Ali, M. Y., Kamaraj, Y., Zhang, Z., Weike, L., Sethupathy, S., & Zhu, D.* (2024). A Comprehensive Review on Biological Funnel Mechanism in Lignin Valorization: Pathways and Enzyme Dynamics. Microbiological Research, 287,127835.
23. Uddin, N., Shinde, H., Ali, N., Zhang, Q., Ullah, R., Iqbal, Z., & Zhu, D.* (2024). Systematic exploration of Ziziphus species collection and gene identification influencing physiological traits using genotype‐by‐sequencing technology. Physiologia Plantarum, 176(4), e14426.
24. Nawaz, M. Z., Khalid, H. R., Shahbaz, S., Al-Ghanim, K. A., Pugazhendhi, A., & Zhu, D.* (2024). Discovery of putative inhibitors of human Pkd1 enzyme: Molecular docking, dynamics and simulation, QSAR, and MM/GBSA. Environmental Research, 257,119336.
25. Ali, M. Y., Mahmoud, A. S., Abdalla, M., Hamouda, H. I., Aloufi, A. S., Almubaddil, N. S., ... & Zhu, D.* (2024). Green synthesis of bio-mediated silver nanoparticles from Persea americana peels extract and evaluation of their biological activities: In vitro and in silico insights. Journal of Saudi Chemical Society, 28(3), 101863.
26. Khazi, M. I., Liaqat, F., Liu, X., Yan, Y., & Zhu, D.* (2024). Fermentation, functional analysis, and biological activities of turmeric kombucha. Journal of the Science of Food and Agriculture, 104(2), 759-768.
27. Xu, Q., Ali, S., Afzal, M., Nizami, A. S., Han, S., Dar, M. A., & Zhu, D.* (2024). Advancements in bacterial chemotaxis: Utilizing the navigational intelligence of bacteria and its practical applications. Science of The Total Environment, 172967.
28. Xu, L., Nawaz, M. Z., Khalid, H. R., Alghamdi, H. A., Sun, J., & Zhu, D.* (2024). Modulating the pH profile of vanillin dehydrogenase enzyme from extremophile Bacillus ligninphilus L1 through computational guided site-directed mutagenesis. International Journal of Biological Macromolecules, 263,130359.
29. Nawaz, M. Z., Alghamdi, H. A., Zahoor, M., Rashid, F., Alshahrani, A. A., Alghamdi, N. S., ... & Zhu, D.*(2024). Synthesis of novel metal silica nanoparticles exhibiting antimicrobial potential and applications to combat periodontitis. Environmental Research, 241, 117415.
30. Uddin, N., Li, X., Ullah, M. W., Sethupathy, S., Ma, K., Elboughdiri, N., ... & Zhu, D.* (2024). Lignin developmental patterns and Casparian strip as apoplastic barriers: A review. International Journal of Biological Macromolecules, 129595.
31. ur Rahman, M., Ullah, M. W., Shah, J. A., Sethupathy, S., Bilal, H., Abdikakharovich, S. A., ... & Zhu, D.* (2024). Harnessing the power of bacterial laccases for xenobiotic degradation in water: A 10-year overview. Science of The Total Environment, 918,170498.
32. Nawaz, M. Z., Xu, C., Qaria, M. A., Haider, S. Z., Khalid, H. R., Alghamdi, H. A., ... & Zhu, D.* (2023). Genomic and biotechnological potential of a novel oil-degrading strain Enterobacter kobei DH7 isolated from petroleum-contaminated soil. Chemosphere, 139815.
33. Shah, S. W. A., Ma, K., Ullah, R., Ali, E. A., Qayum, A., Uddin, N., & Zhu, D.* (2023). Laccase and dye-decolorizing peroxidase-modified lignin incorporated with keratin-based biodegradable film: An elucidation of structural characterization, antibacterial and antioxidant properties. Food Chemistry: X, 101035.
34. Sethupathy, S., Xie, R., Liang, N., Shafreen, R. M. B., Ali, M. Y., Zhuang, Z., ... & Zhu, D.* (2023). Evaluation of a dye-decolorizing peroxidase from Comamonas serinivorans for lignin valorization potentials. International Journal of Biological Macromolecules, 127117.
35. Shah, S. W. A., Xu, Q., Ullah, M. W., Sethupathy, S., Morales, G. M., Sun, J., & Zhu, D.* (2023). Additive manufactured lignin-based Materials: A Review of Current Status, Challenges, and Future perspectives. Additive Manufacturing, 74:103711.
36. Xu, L., Liaqat, F., Sun, J., Khazi, M. I., Xie, R., & Zhu, D.* (2024). Advances in the vanillin synthesis and biotransformation: A review. Renewable and Sustainable Energy Reviews, 189, 113905. (ESI高被引论文)
37. Qaria, M. A., Xu, C., Hussain, A., Nawaz, M. Z., & Zhu, D.* (2023). Metagenomic investigations on antibiotic resistance and microbial virulence in oil-polluted soils from China. Environmental Science and Pollution Research, 1-10.
38. Uddin, N., Li, X., Muhammad, N., Ullah, R., Bari, A., Khan, K. A., ... & Zhu, D.* (2024). Identification and diversity assessment of Ziziphus species using DNA barcoding. Scientia Horticulturae, 323, 112544.
39. Khazi, M. I., Liaqat, F., Liu, X., Yilin, Y., & Zhu, D.* (2023). Fermentation, functional analysis and biological activities of turmeric kombucha. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.12962.
40. Liaqat, F., Xu, L., Khazi, M. I., Ali, S., Rahman, M. U., & Zhu, D.* (2023). Extraction, purification, and applications of vanillin: A review of recent advances and challenges. Industrial Crops and Products, 204, 117372. (ESI高被引论文)
41. Ali, M. Y., Liaqat, F., Khazi, M. I., Sethupathy, S., & Zhu, D* (2023). Utilization of glycosyltransferases as a seamless tool for synthesis and modification of the oligosaccharides-A review. International Journal of Biological Macromolecules, 249:125916.
42. Mutanda, I., Sivasamy, S., Xu, Q., Zhu, B., Shah, S. W. A., Zhuang, Z., & Zhu, D*. (2023). Optimization of heterologous production of Bacillus ligniniphilus L1 laccase in Escherichia coli through statistical design of experiments. Microbiological Research, 274,127416.
43. Nazar, M., Xu, Q., Ullah, M. W., Khan, N. A., Iqbal, B., & Zhu, D*. (2023). Integrated laccase delignification with improved lignocellulose recalcitrance for enhancing enzymatic saccharification of ensiled rice straw. Industrial Crops and Products, 202, 116987.
44. Xu C, Majjid A. Qaria, Xu Q, Zhu, D*. (2023) The role of microorganisms in petroleum degradation: Current development and prospects, Science of The Total Environment, 865, 161112.
45. Gabriel Murillo-Morales, Sivasamy Sethupathy, M Zhang, L Xu, Amirreza Ghaznavi, J Xu, B Yang, J Sun, Zhu, D*. (2023) Characterization and 3D printing of a biodegradable polylactic acid/thermoplastic polyurethane blend with laccase-modified lignin as a nucleating agent, International Journal of Biological Macromolecules, 236, 123881.
46. Zahoor, Madadi, M., Nazar, M., Shah, S. W. A., Li, N., Imtiaz, M., Zhong, Z., & Zhu D*. (2023). Green alkaline fractionation of sugarcane bagasse at cold temperature improves digestibility and delignification without the washing processes and release of hazardous waste. Industrial Crops and Products, 200, 116815.
47. Nawaz MZ, Shang H, Sun J, Geng A, Ali SS, Zhu D*. (2023). Genomic insights into the metabolic potential of a novel lignin-degrading and polyhydroxyalkanoates producing bacterium Pseudomonas sp. Hu109A. Chemosphere, 310,136754.
48. Berhanu A, Mutanda I, Taolin J, Qaria MA, Yang B, Zhu D* (2023). A review of microbial degradation of per- and polyfluoroalkyl substances (PFAS): Biotransformation routes and enzymes. Science of The Total Environment,10,859. (ESI高被引论文)
49. Qaria, M. A., Xu, C., Hu, R., Alsubki, R. A., Ali, M. Y., Sivasamy, S., ... & Zhu, D*. (2023). Ectoine Globally Hypomethylates DNA in Skin Cells and Suppresses Cancer Proliferation. Marine Drugs, 21(12), 621.
50. Mutanda, I., Sun, J., Jiang, J., & Zhu, D*. (2022). Bacterial membrane transporter systems for aromatic compounds: Regulation, engineering, and biotechnological applications. Biotechnology Advances, 59, 107952.
51. Zhu, D*., Qaria, M. A., Zhu, B., Sun, J., & Yang, B. (2022). Extremophiles and extremozymes in lignin bioprocessing. Renewable and Sustainable Energy Reviews, 157, 112069.
52. Nazar, M., Xu, L., Ullah, M. W., Moradian, J. M., Wang, Y., Sethupathy, S., & Zhu, D*. (2022). Biological delignification of rice straw using laccase from Bacillus ligniniphilus L1 for bioethanol production: A clean approach for agro-biomass utilization. Journal of Cleaner Production, 360, 132171.
53. Sethupathy, S., Morales, G. M., Gao, L., Wang, H., Yang, B., Jiang, J., ... & Zhu, D*. (2022). Lignin valorization: Status, challenges and opportunities. Bioresource Technology, 347, 126696. (ESI高被引论文)
54. Zhu, D*., Sethupathy, S., Gao, L., Nawaz, M. Z., Zhang, W., Jiang, J., & Sun, J. (2022). Microbial diversity and community structure in deep-sea sediments of South Indian Ocean. Environmental Science and Pollution Research, 29, 45793-45807.
55. Nawaz, M. Z., Attique, S. A., Ain, Q. U., Alghamdi, H. A., Bilal, M., Yan, W., & Zhu, D*. (2022). Discovery and characterization of dual inhibitors of human Vanin-1 and Vanin-2 enzymes through molecular docking and dynamic simulation-based approach. International Journal of Biological Macromolecules,213(31),1088-1097.
56. Zhu, D*., Xu, L., Sethupathy, S., Si, H., Ahmad, F., Zhang, R., ... & Sun, J. Z. (2021). Decoding lignin valorization pathways in the extremophilic Bacillus ligniniphilus L1 for vanillin biosynthesis. Green Chemistry, 2021, 23, 9554-9570.
57. Li, Y., Qaria, M.A., Sethupathy, S., Sun, J., & Zhu, D*.(2021). Curcumin production and bioavailability: A comprehensive review of curcumin extraction, synthesis, biotransformation and delivery systems. Industrial Crops and Products, 172, 114050.
58. Sethupathy, S., Morales, G. M., Li, Y., Wang, Y., Jiang, J., Sun, J., & Zhu, D*. (2021). Harnessing microbial wealth for lignocellulose biomass valorization through secretomics: a review. Biotechnology for Biofuels, 14(1), 1-31.
59. Fiaz, A., Zhu, D*., & Sun, J*. (2021). Environmental fate of tetracycline antibiotics: degradation pathway mechanisms, challenges, and perspectives. Environmental Sciences Europe, 33(1), 1-17. (ESI高被引论文)
60. Zhu, D*., Liang, N., Zhang, R., Ahmad, F., Zhang, W., Yang, B., ... & Sun, J*. (2020). Insight into depolymerization mechanism of bacterial Laccase for lignin. ACS Sustainable Chemistry & Engineering, 8(34), 12920-12933.
61. Zhu, D*., Adebisi, W. A., Ahmad, F., Sethupathy, S., Danso, B., & Sun, J*. (2020). Recent development of extremophilic bacteria and their application in biorefinery. Frontiers in Bioengineering and Biotechnology, 8, 483.
62. Ahmad, F., Zhu, D*., & Sun, J. (2020). Bacterial chemotaxis: a way forward to aromatic compounds biodegradation. Environmental Sciences Europe, 32(1), 1-18.
63. Morales, G. M., Ali, S. S., Si, H., Zhang, W., Zhang, R., Hosseini, K., ... & Zhu, D*. (2020). Acidic Versus Alkaline Bacterial Degradation of Lignin Through Engineered Strain E. coli BL21 (Lacc): Exploring the Differences in Chemical Structure, Morphology, and Degradation Products. Frontiers in bioengineering and biotechnology, 8, 671.
编辑及客座编辑
1. Associate Editor, Heliyon, Elsevier.
2. Associate Editor, Frontiers in Microbiology, Frontiers Media S.A.
3. Editorial board member, Sustainable Processes Connect, SCIFINITI
4. Guest Editor, Insect Science. Wiley
5. Guest Editor, Frontiers in Bioengineering and Biotechnology.
6. Guest Editor, Frontiers in Soil Science.
7. Guest Editor, Toxics, MDPI
8. Guest Editor, Gels MDPI
编著
1. Shahnawaz, M., Sangale, M.K., Daochen, Z., Ade, A.B. (2021) Impact of Plastic Waste on the Marine Biota (Eds.) Springer Nature Singapore Pte Ltd. https://link.springer.com/book/10.1007/978-981-16-5403-9
2. Shahnawaz, M., Adetunji, C. O., Dar, M. A., & Zhu, D. (Eds.). (2024). Microplastic Pollution. Springer Nature Singapore, Imprint: Springer.https://link.springer.com/book/10.1007/978-981-99-8357-5.
3. Daochen Zhu, Mudasir Ahmad Dar, Mohd. Shahnawaz. (Eds.). (2024). Biofuels and Sustainability: Life Cycle Assessments, System Biology, Policies, and Emerging Technologies, Elsever. Biofuels and Sustainability: Life-Cycle Assessments, System Biology, Policies, and Emerging Technologies (Woodhead Bioenergy) | mitpressbookstore
4. Osikemekha Anthony Anani, Mohd. Shahnawaz, Mudasir Ahmad Dar, Zhu Daochen. (Eds.). (2024). Plastic and the COVID-19 Pandemic: Innovative Solutions to Mitigate Plastic Pollution. Springer Nature Switzerland.
5. Nikalje, G. C., Shahnawaz, M., Parihar, J., Qazi, H. A., Patil, V. N., & Zhu, D. (Eds.). (2024). Plant Secondary Metabolites and Abiotic Stress. John Wiley & Sons.
部分发明专利
1、 朱道辰，孙建中，谢长校，李成林，张佩佩，一种红球菌及其在降解木质素方面的应用，2017-10-20，ZL201510010883.9
2、 朱道辰，谢长校，孙建中，李成林，张佩佩，一种深海微小杆菌及其在降解有机污染物中的应用，2018-02-27，ZL201510010845.3
3、 朱道辰，张佩佩，孙建中，一种过氧化物酶DyP35基因及其表达蛋白和应用，2020-01-24, ZL201710666640.X
4、 朱道辰，张佩佩，一种降解农业废弃物的复合菌剂，2020-05-05, ZL201710024924.9
5、 朱道辰, 陈焱, 孙建中,李奕萱，一种含木质素类生物质转化合成姜黄素的方法，2020-09-23，中国, ZL 202011009212. 8, PCT/CN2020/126907.，2020-11-06
6、 朱道辰,李奕萱， 姚明迅, 陈焱, 王倩茹, 孙亚如，一种糖基化姜黄素促进伤口愈合水凝胶敷料的制备方法及其应用, ZL202211500195.7，2022-11-28，
7、 朱道辰, 孙建中, 加布里埃尔•穆里洛•莫拉莱斯, 徐春艳，一种含有酶改性木质素的热塑性长丝及其制备方法和应用，ZL202111214435.2，2021-10-19
8、 朱道辰，徐春艳，韩序，郝伟，一种高效石油降解菌株及其应用，ZL202210240509.8，2022/03/10
